• In summary our study has revealed

  2020-08-03

  

  In summary, our study has revealed that CK2 positively regulates Msn2 activity in a phosphorylation-dependent manner in response to H2O2, and lactic acid, and glucose starvation. These findings shed light on the crucial role for CK2 as a central regulator administering not only growth-related but al

• br Results and discussions In general experimental analysis

  2020-08-03

  

  Results and discussions In general, experimental analysis is time consuming and expensive. Thus, In the present study, Taguchi design of experiments (DOE) was adopted to reduce the number of trials. To analyze the data, a High Level Analysis (HLA) is performed by averaging measured data for each

• br Introduction Historically eukaryotic protein glycosylatio

  2020-08-03

  

  Introduction Historically, eukaryotic protein glycosylation was thought to occur exclusively in the endoplasmic reticulum and Golgi apparatus as part of the secretory pathway, which produces a vast array of diverse membrane glycoproteins. In the mid-1980s, however, Hart et al. found O-linked β-N-

• br Discussion We have demonstrated that ER stress induced se

  2020-08-03

  

  Discussion We have demonstrated that ER stress-induced sensors and mediators of the UPR are stimulated by OT-alone or in combination with LPS, whereas many of these same markers are inhibited by LPS alone, as summarized in Table 1. The dynamic upregulation of OTR microcystin lr in the gut during

• br Experimental section br Acknowledgments This

  2020-08-03

  

  Experimental section Acknowledgments This research was supported by statutory funds of CMMS PAS in Lodz. Authors want to thank Ms. Barbara Mikolajczyk for all the help in HPLC analysis and Prof. Piotr Guga for fruitful discussion. Introduction DNA ligases play an essential role in maintain

• br Experimental br Author contributions br

  2020-08-03

  

  Experimental Author contributions Acknowledgement Introduction Microalgae represent an outstanding natural source of biochemically active metabolites [1].These algae-derived products, such as polyunsaturated fatty acids, have significant potential for applications in numerous industrial

• At present there have been

  2020-08-03

  

  At present, there have been no studies on the relationship between CYP2D6 gene polymorphism and the lipid-lowering effect of atorvastatin. Our results showed that the rs1065852 in CYP2D6 influences the effectiveness of atorvastatin, and the GG genotype had a better response to atorvastatin therapy,

• Materials and Methods br Discussion BMG is a

  2020-08-01

  

  Materials and Methods Discussion BMG is a complex multifactorial condition in which the contribution of each factor remains unclear. Several studies3, 4, 5, 6, 7 have sought to show the associations among the clinical, psychological, immunologic, and genetic parameters. These studies where perfo

• Apigenin trihydroxyflavone is a flavone that has been detect

  2020-07-31

  

  Apigenin (4′,5,7-trihydroxyflavone), is a flavone that has been detected in a wide range of fruits, and vegetables such as bell pepper celery and cabbage. This natural flavonoid covers a broad spectrum of pharmacological activities in regard to antioxidant, anti-mutagenic, sedative, anxiolytic, and

• It has only recently been appreciated that antigen activated

  2020-07-31

  

  It has only recently been appreciated that antigen-activated Gliotoxin undertake two additional transient migrations during the early stages of T-dependent antibody responses. In the first of these, antigen-activated B cells migrate rapidly (within 2–3h) to the outer regions of the follicle before

• br MARCH E ligases A specific family of eukaryotic E

  2020-07-31

  

  MARCH E3 ligases A specific family of eukaryotic E3 ligases that has received additional attention recently consists of the embrane-ssociated ING- (MARCH) proteins. Initially, two viral MARCH-homologue gene products were discovered in Kaposi\'s sarcoma (KS)-associated herpesvirus (KSHV), and subs

• br Materials and Methods br Acknowledgements

  2020-07-31

  

  Materials and Methods Acknowledgements Authors would like to thank Mr. Pritam Naskar and Mr. Dibya Mukherjee for their help. Authors also acknowledge the help of Mr. Barun Mahata and Dr. Kaushik Biswas, Division of Molecular Medicine, Bose Institute, for human cDNA samples. P.A.B. and A.B.D. w

• In addition to supporting the catalytic

  2020-07-31

  

  In addition to supporting the catalytic function of BRCC36, KIAA0157 and Abraxas also serve scaffolding functions to recruit the BRCC45–MERIT40 heterodimer and the targeting subunits RAP80 or SHMT2. Surprisingly, super dimerization is not only required for the catalytic function of BRCC36 but it is 

• Previously the difference in fluorescence between the fillin

  2020-07-31

  

  Previously, the difference in fluorescence between the filling and the tooth under ultraviolet light has been suggested as an adjunct method [21,22]. However, the industry has tried to match their fluorescence, impairing the detection of the materials by ultraviolet lights [23]. Bux et al. [24] demo

• Comet assay is a widely accepted method

  2020-07-31

  

  Comet assay is a widely accepted method for assessing DNA damage in individual cells. It can be used to measure single-strand or double-strand DNA breaks, alkali labile sites, DNA crosslinks, base/base-pair damages and apoptotic cells. This method was introduced by Ostling and Johanson [2] in 1984,

14778 records 792/986 page Previous Next First page 上5页 791792793794795 下5页 Last page