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br Model Fig demonstrates the block scheme
2023-06-27

Model Fig. 1 demonstrates the block-scheme of main interactions between variables of the model under investigation. These interactions are described below in details and are expressed in mathematical form as well, where all variables are the functions of space and time coordinates, r and t, which
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Rising depolarization was observed during
2023-06-19

Rising depolarization was observed during and decaying depolarization after the photostimulation (Fig. 1D). The slow decrease of the firing rate after photostimulation is also a remarkable characteristic of the striatal neuron (Figs. 1E, 2 and 3), since the cortex pyramidal neurons (data not shown)
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Interestingly our transgenic mouse model with macrophages
2023-06-19

Interestingly, our transgenic mouse model with macrophages expressing AdipoR1 showed not only improved insulin sensitivity and inflammation in skeletal muscle and adipose tissues, but fat mass, macrophage and plasma lipid accumulation and foam cell formation was also favorably reduced resulting from
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It is important to note that
2023-06-14

It is important to note that stable amnesia is, apparently, a general biological phenomenon and can be found in different animal species. In studies on rats, it was found that if reconsolidation of conditioned olfactory aversion memory was impaired by the antagonist of NMDA glutamate receptors, amne
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During the year study period of
2023-06-14

During the 4-year study period, 19.9% of men in the dutasteride group developed prostate cancer as compared to 25.1% in the placebo group, which represents an absolute risk Topiroxostat of 5.1% for men taking dutasteride (Pe weighed against the prospect of undesirable sexual side effects and decrea
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br Experimental procedure br Introduction Migraine is a debi
2023-06-14

Experimental procedure Introduction Migraine is a debilitating neurovascular disorder characterized by recurring unilateral pulsating headaches of moderate to severe intensity, associated with nausea, photophobia and/or phonophobia, lasting from 4 to 72 h (Headache Classification Committee of
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Methoxyresorufin receptor br Autophagy and antiviral innate
2023-06-13

Autophagy and antiviral innate immunity signaling Viral manipulation of autophagy interfering with IFN-I synthesis We have seen that autophagy factors can down-regulate the production of IFN-I induced by RLR engagement during viral infection. In fibroblasts and epithelial cells, there exists c
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In the present study we sought to decipher
2023-06-13

In the present study we sought to decipher the role of ATP-citrate lyase and of the mitochondrial NADH-dependent Mae in the oleaginous yeast Y. lipolytica. Indeed, although this yeast is one of the major models for lipid metabolism, the function of these enzymes is still not clear. As the study of t
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The electrokinetic remediation technique is carried out with
2023-06-07

The electrokinetic remediation technique is carried out with a low-level direct current, and the pollutants in soil can be transported and removed by the electric field [19]. This works well even in soil with low permeability via electro-osmotic flow and electro-migration [20]. The electrokinetic pr
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Use of RASB is associated with potential concerns
2023-06-07

Use of RASB is associated with potential concerns about side effects such as acute kidney injury or hyperkalemia, and clinicians are reluctant to prescribe RASB in patients with severe renal dysfunction (estimated GFR Conclusions Conflict of interest Acknowledgement Introduction Renin-an
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HsALDH enzyme has been purified for the first time in
2023-06-03

HsALDH enzyme has been purified for the first time in our laboratory from human saliva and has been kinetically characterized using different aromatic substrates [35]. Also, the effect of some common substances frequently encountered by the enzyme in the oral cavity (such as ethanol, hydrogen peroxi
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br ACK inhibitors Since ACK activation is correlated
2023-05-31

ACK1 inhibitors Since ACK1 activation is correlated with poor prognosis in various cancers, strong efforts are being directed by multiple groups towards developing highly potent and specific small molecule inhibitors targeting the ACK1 kinase. At least eight small molecule kinase inhibitors have
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The purpose of this study is to
2023-05-30

The purpose of this Quinidine australia study is to examine the relationship between ACEs and engagement in treatment among a sample of youth in residential treatment centers (RTCs). It is hypothesized that youth with higher ACE scores will have lower levels of engagement in treatment. In order to
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The discovery of acetylsalicylic acid aspirin in paved the w
2023-05-30

The discovery of acetylsalicylic p-Chlorophenylalanine (aspirin) in 1897 paved the way for the development of classical NSAIDs as first-line therapeutics for anti-inflammatory, anti-pyretic and analgesic therapy. Large efforts have been made in the following decades to improve the efficacy and in p
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We found that several anticancer drugs inhibit
2023-05-30

We found that several anticancer drugs inhibit 5-HT3 Clotrimazole current in vitro. Several studies have suggested that 5-HT3 receptor antagonists have anti-mitogenic and apoptotic effects on colorectal and breast cancer cell lines (Ataee et al., 2010, Hejazi et al., 2015). Irinotecan is used frequ
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